Careers

Our Employment Philosophy

Because the quality of Otonomy’s employees is the key to our success, we carefully select each new employee. We are committed to developing products that will benefit people’s lives and build value for our shareholders. As a team, we value honesty and integrity, knowledge, initiative and leadership, and a commitment to quality and improvement in everything we do. We want our decisions and actions to demonstrate these values. We treat one another with respect and take pride in the significant contributions that come from teamwork and the diversity of our organization.  We strive for excellence and sound, responsible decision making. We know that Otonomy’s success depends on the performance of each member of our team.

When filling open positions, we will always strive to select the most qualified candidate regardless of race, color, religion, sex, national origin, ancestry, age, medical condition, sexual orientation, marital status, pregnancy, physical or mental disability, veteran or other protected status. We are proud to be an Equal Opportunity Employer with commitment to Affirmative Action for Minorities, Women, Individuals with Disabilities and Veterans.

Current Openings

Research

Scientist, Drug Target Biology

The Scientist, DTB will create a capability that enables the investigation of therapeutic targets and candidate molecules in cochlea cells and tissue using molecular, biochemical and electrophysiological techniques to support the growth of Otonomy’s pipeline.  Design, develop and validate biomarkers to support the company’s applied translational research, target selection, and clinical development efforts in ear diseases.

Requirements includes a Ph.D. in Molecular Biology, Cell Biology, Pharmacology, Neuroscience, or related discipline.  Qualified candidates will also have 5+ years of experience in a comparable role with a biotechnology or pharmaceutical company required.  Comprehensive knowledge of current practices in in vitro cell and molecular biology and pharmacology research within Neuroscience, Ophthalmology and/or Otology.  Experience in developing testing models for drug target characterization and validation, with a desire and experience in translating new biology into viable therapeutics a plus.  Expertise in assay development, automation of assays, and state-of-the-art molecular and biochemical techniques. Experience writing and submitting reports in support of regulatory submissions (INDs). A primary focus and experience in signaling and regulatory pathways, pharmacology or neuroscience is preferred.  A commitment to high-quality research and the execution of research plans in a timely and organized manner.  Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to interact effectively with collaborators, clients, vendors and personnel, who may have different levels of technical knowledge and understanding.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Associate Scientist, Biology

The Associate Scientist will contribute to the investigation of therapeutic targets and candidate molecules in cochlea cells and tissue using molecular, biochemical and electrophysiological techniques to support the growth of Otonomy’s pipeline.  Develop biomarkers to support the company’s applied translational research, target selection, and clinical development efforts in ear diseases.  Develop, and execute in vitro biochemical molecular and cell based assays in support of applied drug discovery and development.  Develop and validate testing models to assess drug-able pathways of human ear disease to evaluate the efficacy of small molecule drug candidates and to facilitate selection of relevant ear diseases for preclinical and clinical evaluation.  Conduct biomarker studies of candidate drugs in animal models in close collaboration with the Preclinical Group.

Requirements include a BS/BA. in Biology, Molecular Biology, Cell Biology, Pharmacology, Neuroscience, or related discipline or the equivalent education and experience.  Qualified candidates must also have 5+ years of experience in a comparable role with a biotechnology or pharmaceutical company required.  Comprehensive knowledge of current practices in in vitro cell and molecular biology and pharmacology research within Neuroscience, Ophthalmology and/or Otology.  Experience in developing testing models for drug target characterization and validation, with a desire and experience in translating new biology into viable therapeutics a plus.  Expertise in assay development, automation of assays, and state-of-the-art molecular and biochemical techniques. Experience writing and submitting reports in support of regulatory submissions (INDs). A primary focus and experience in signaling and regulatory pathways, pharmacology or neuroscience is preferred.  A commitment to high-quality research and the execution of research plans in a timely and organized manner.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Scientist, Formulations Development

The Scientist will design, conduct, analyze and report on formulation and process development quality-by-design experiments in Formulation Development. Lead technical efforts in characterization and optimization of exploratory formulations and process design space definition for late stage drug products. Support pre-clinical efforts by designing and conducting laboratory studies relating to formulation performance, stability, process and product characteristics. Actively participate in generating data and reports to support new candidate assessment, new drug delivery system development, IND, NDA and other regulatory filings.

Requirements include a Ph.D. degree in Pharmaceutical Sciences or a related discipline, or an equivalent level of knowledge and experience.  In addition, 1-3+ years’ experience post-Ph.D. degree.  Experience to include designing, implementing and assessing pharmaceutical formulations and product performances to validate research and/or development hypotheses or findings.  Hands-on knowledge, experiences and training in polymer based parenteral drug delivery technologies, polymer characterization and peptide/protein formulation development are strongly preferred.  Relevant industry experience is a plus.  Excellent analytical and problem solving skills required. A personal sense of accountability for furthering the Company’s mission is essential.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Regulatory and QA

Regulatory Affairs Manager

The R/A Manager will lead the coordination of all administrative activities needed in the development, submission and tracking of regulatory filings associated with NDA post-approval activities.  Participate in the development and implementation of regulatory strategies, policies and procedures. Research regulatory guidance and precedence for Otonomy commercial support and make recommendations on approach as requested.  Serve as regulatory representative on the Promotional Review Committee. Coordinate the preparation of all post-approval regulatory submissions (e.g., NDA supplements, promotional material, drug listings, periodic safety and annual reports).  Prepare training materials and train internal customers on various regulatory compliance issues associated with post-marketing activities (e.g., pharmacovigilance, periodic safety reporting, promotion).

Requirements include a Bachelors’ degree in a scientific discipline or the equivalent education and experience as well as 5+ years of relevant experience in the pharmaceutical or biotech industry.  Must have familiarity with submissions to the FDA, specifically in support of post-marketing activities.  EU experience a plus.   Knowledge in project management practices and tools and the overall drug development process necessary.  Must have background working in the interdisciplinary team environment.  Strong verbal and written communication skills and detail orientation required. Must be proactive, independent, hard-working and committed to achieving difficult goals.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Pharmaceutical Development

Sr. Scientist/Manager – Analytical Chemistry

This individual will develop and execute directly and through staff the Company’s Analytical Development efforts to support pre-formulation, formulation, process development, and clinical supply and CMC requirements. Develop phase appropriate methods to support Otonomy’s development programs. Transfer methods to contract labs and manage related technical activities including ongoing and new stability programs. Assist in preparing CMC input and documents for regulatory submissions.

Requirements include a Ph.D. degree in Analytical Chemistry or related disciplines or the equivalent education and experience.  Qualified candidates must have in-depth scientific knowledge and hands-on relevant industry experience of at least 5-7+ years in the development and validation of analytical methods. Hands-on experience in more than one of the following techniques is a must: HPLC, UPLC, GC, SEC, Particle Size, Mass Spectrometry, and Dissolution.  Hands-on experience with effectively managing external contract sites is a must.  Ability to exercise independent judgment in developing methods and evaluation criteria needed to obtain results is required

Must have excellent working knowledge of cGMP practices, ICH Quality Guidelines and other regulatory requirements.  Good knowledge of solid state characterization (e.g. XRPD, IR, NMR, Adsorption Isotherm, DSC, TA, Surface Area Measurement, Particle Size Measurement, and Flow Properties) is a plus as is familiarity with characterization of sustained and controlled release formulation.  Must have experience in completing quality sections for regulatory submissions

To Apply

Please send your resume with salary requirements to humanresources@otonomy.com
or mail to 6275 Nancy Ridge Drive, Suite 100, San Diego, CA 92121, attention Human Resources.  Please note job code SSMBS15.

Manager, Quality Control

The manager will oversee method validation and method transfers for late stage (Phase 2 through commercialization) development programs performed at contract organizations.   Develop and oversee stability programs conducted to support later stage clinical development programs and regulatory filings. Lead method transfer activities between contract testing labs and/or contract manufacturing organizations to support manufacturing and release of drug products, drug substances and raw materials as required.  Oversee stability programs at contract testing labs, including ICH registration stability studies and commercial products stability programs. Perform technical review of data, provide stability summaries and trends for regulatory submissions.

Requirements include a B.S. or M.S degree in Pharmaceutical Sciences or a related discipline, or the equivalent education and experience.  Qualified candidates must also have at least ten (10) years’ experience in pharmaceutical drug development specifically, analytical development and QC.At least 5 years of experience working with contract test laboratories on stability programs and method validation activities. Experience in managing ICH registration stability studies, release and stability testing of commercial drug products is preferred. Hands on experience and a solid understanding of a variety of analytical methods, and regulatory guidelines related to method validation and transfers.   Excellent analytical and problem solving skills are required. Excellent verbal and writing skills are essential.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Medical

Vice President, Medical Affairs

The VP, Medical Affairs will develop, execute and communicate the Medical Affairs strategy for all compounds in development at Otonomy to ensure that the Otolaryngology and broader commercial community is appropriately educated and enthusiastic about the clinical and scientific basis for the science, therapeutic application and clinical research behind Otonomy’s product portfolio.  Establish Key Opinion Leader (KOL) engagement objectives.  Develop and maintain relationships and educate KOLs in all matters critical to successful KOL support for Otonomy’s programs.  Establish the strategy around the composition and use of Medical Advisory Boards and Medical Advocacy activities.

Requirements include an M.D. with relevant board certifications and 10+ years of experience in a comparable role with a biotechnology or pharmaceutical company required.  In addition, must have clinical trial experience, in academics, cooperative groups and/or industry.  Must have proven success developing and maintaining fruitful KOL relationships and a solid understanding of the commercial drivers of pharmaceutical success.  Proven experience setting strategy and implementing operational plans is important.   Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to interact effectively with collaborators, clients, vendors and personnel, who may have different levels of technical knowledge and understanding.  Current knowledge of and experience with the latest best practices in the Otolaryngology field is preferred.  Incumbent will be capable of implementing new ideas, programs and motivating staff to produce effective results, while working in a start- up “roll-up-the-sleeves” working environment.  Professional demeanor is expected at all times, including the ability to remain thoughtful and focused under pressure.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Sr. Director, Medical Operations

The Sr. Director, Medical Operations will develop, execute and communicate the strategy, processes and procedures for the Medical Operations department; responsible for developing, overseeing and optimizing all processes, training, SOPs and systems in relation to the overall Medical function, including data management. Establish and manage the Medical Information and Communication role as well as the Medical Writing role and the execution of abstracts, posters, manuscripts and secondary analysis.  Ensure the Medical division is compliant with Sunshine Act, Pharma Code and other OIG and FDA compliance regulations. Coordinate activities with all other functions responsible companywide.  Participate in the creation of Otonomy’s global publication plan, medical education calendar and partner/sales/medical professional training program, in conjunction with Otonomy’s Commercial organization and other relevant parties.   Lead the implementation of the plan.  Plan and oversee all journal and congress executional strategies and planning activities companywide.

Requirements include an M.D., Ph.D., Pharm.D., or M.S. with relevant board certifications along with 8+ years of experience in an applicable role with a biotechnology or pharmaceutical company required. Must have experience setting and carrying out initiatives in Medical Operations, Publications and Communications with a strong focus on KOL development and clinical/commercial dynamics. Experience communicating clinical trial results and engaging KOLs, academics, cooperative groups and/or industry needed.  Proven experience setting strategy and implementing operational plans is important. Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to interact effectively with collaborators, clients, vendors and personnel, who may have different levels of technical knowledge and understanding. Incumbent will be capable of implementing new ideas, programs and motivating staff to produce effective results, while working in a start- up “roll-up-the-sleeves” working environment. Professional demeanor is expected at all times, including the ability to remain thoughtful and focused under pressure.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Commercial

Director, Sales Operations

Responsible for developing, communicating, overseeing and optimizing programs in relation to the Commercial organization’s Sales Operations efforts including sales performance metrics, sales headcount and budget resources, incentive compensation, CRM, Master data management (MDM), fleet, field communications and Compliance (Sunshine Reporting)

Requirements include a Bachelor’s degree (business preferred) or an equivalent combination of relevant education and applicable job experience may be considered.  MBA highly desirable. In addition, a minimum of 10 years of experience in the pharmaceutical industry in a variety of progressively responsible commercial roles, preferably within the areas of commercial analytics, sales operations, market research, sales or marketing, and at least 2 years in management roles.  Familiarity with analytical methods and approaches specific to pharmaceutical sales and marketing is required, as is experience in the use of data management and presentation tools (Excel, Access, and PowerPoint).  Expertise in analyzing secondary data in the pharmaceutical industry and a working knowledge of statistical processes and software (e.g. SAS, SPSS, R) is a plus.  Capable of implementing new ideas, programs and motivating others to produce effective results, while working in a fast-paced, “roll-up-the-sleeves” working environment.  Must also be skilled at multi-tasking and leading cross-functional project teams.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge, Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer

Clinical Development

Head of Biostatistics

Incumbent will develop, execute and communicate the Biostatistics strategy for all Otonomy compounds to ensure that studies are designed and analyzed to achieve clinical development goals, and that the Otolaryngology and broader commercial community is appropriately educated and enthusiastic about the science and therapeutic applications within the Otonomy product portfolio. The Head of Biostatistics is expected to provide hands on statistics support on an as needed basis.  Work with project team to decide on appropriate study design and statistical methodology for routine designs, and provide protocol input, randomization schedule, and guidance on database activities.  Responsible for protocol review with the clinical team, and assist in the development and advancement of the randomization schedule, sample size and power calculations.  Responsible for protocol statistical methods and provide assistance to CROs in the development of the Statistical Methods section in clinical study protocols.

Requirements include a Ph.D., Pharm.D., or M.S. with relevant board certifications or the equivalent education and experience.  Qualified candidates will have 8+ years of experience in a comparable role with a biotechnology or pharmaceutical company required, as well as experience working with CROs.  High degree of technical competence and communicative ability, both oral and written.  Competent in experimental design, descriptive and inferential statistics, biometrics and computer systems.  Must have pharmaceutical or related industry experience with clinical trials, including interaction with Regulatory Agencies, especially FDA and ICH guidelines.  Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to interact effectively with collaborators, clients, vendors and personnel, who may have different levels of technical knowledge and understanding.

To Apply

Please send your resume with salary requirements to humanresources@otonomy.com
or mail to 6275 Nancy Ridge Drive, Suite 100, San Diego, CA 92121, attention Human Resources.  Please note job code BSTBS5.

Business Operations

Executive Assistant

This position provides administrative/secretarial support to the Chief Executive Officer, Chief Financial Officer and the Chief Commercial Officer involving the coordination of highly complex details and completion of advanced administrative duties.  The E/A will prepare, review, edit and revise correspondence, presentations, spreadsheets and graphs utilizing word processing, spreadsheet and desktop publishing software; transcribe information of a technical and/or sensitive nature; may be required to take meeting and/or conference call minutes; interact with counterparts of Board members and other key external executives to execute duties; coordinate meetings and conference calls by preparing agendas and the meeting space, monitoring attendee needs during the meeting; maintain calendar(s), complete travel requests, greet visitors and oversee their visit; research, compile and summarize information to formulate correspondence and respond to various inquiries from internal and external customers and complete and manage on-going project assignments including but not limited to document processing, report compilation and event coordination to support the assigned executive’s efforts.

Requirements include a bachelor degree in Business Administration, Human Resources or a related discipline, or the equivalent knowledge and experience preferred.  Qualified candidates will also a minimum of five years of highly applicable experience working with a CEO and/or other top executives handling a variety of complex and sensitive issues.  Must demonstrate exceptional computer skills and relevant software application proficiency.

How to Apply:

Please send your resume to humanresources@otonomy.com or mail to Otonomy, Inc. at 6275 Nancy Ridge Drive, Suite 100, San Diego, CA 92121.

Otonomy is an Equal Opportunity Employer.

To Apply

Please send your resume with salary requirements to humanresources@otonomy.com
or mail to 6275 Nancy Ridge Drive, Suite 100, San Diego, CA 92121, attention Human Resources.

Otonomy is an Equal Opportunity Employer